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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T36254 | dTAGV-1 hydrochloride | ||
Hydrochloride salt of dTAGV-1. Suitable for use in vivo. Following ip administration of 10 mg/kg in mice: T = 4.43 h; Cmax = 2123 ng mL-1; AUCinf = 18517 hr*ng mL-1 and CL = 9.05 mL min-1 kg-1 Negative control dTAGV-1-... | |||
T36253 | dTAGV-1 | ||
Degrader targeting mutant FKBP12F36V fusion proteins. Comprises a ligand selective for F36V single-point mutated FKBP12, a linker and a von Hippel-Lindau (VHL)-binding ligand. Induces potent and selective degradation of ... | |||
T36255 | dTAGV-1-NEG | ||
Negative control for dTAGV-1. | |||
T40251 | dTAGV-1 TFA | ||
dTAGV-1 TFA is a highly effective and specific compound that targets mutant FKBP12 F36V fusion proteins for degradation. It possesses potent activity in inducing the degradation of the FKBP12 F36V -Nluc protein in living... | |||
T74412 | dTAGV-1-NEG TFA | ||
dTAGV-1-NEG TFA, a diastereomer, serves as the heterobifunctional negative control for dTAGV-1. It acts specifically as an FKBP12 F36V-selective degrader [1]. |